Significant New Activity Review groups

The tables below contain lists of substances included in each Significant New Activity (SNAc) Review group. Chemical Abstract Service Registry Numbers (CAS RNs) or confidential identifiers are indicated where available.

For more information, read about the SNAc Review process or consult the SNAc publications under the Canadian Environmental Protection Act, 1999.

Aromatic Azo and Benzidine-based Substances SNAc Review Group
CAS RN Chemical substances Review status
1229-55-6 Solvent Red 1 Under review
1871-22-3 2H-Tetrazolium, 3,3'-(3,3'-dimethoxy[1,1' -biphenyl]-4,4'-diyl)bis[2,5-diphenyl-, dichloride Rescinded – March 2015
1937-37-7 Direct Black 38 Under review
2537-62-4 Acetamide, N-[2-[(2-bromo-6-cyano-4-nitrophenyl)azo]-5-(diethylamino)phenyl]- Rescinded - July 2017
2653-64-7 2-Naphthalenol, 1-(1-naphthalenylazo)- Rescinded - October 2016
3118-97-6 Solvent Orange 7 Under review
3701-40-4 2,7-Naphthalenedisulfonic acid, 4-hydroxy-3-[[4'-[(2-hydroxy-1-naphthalenyl)azo]-2,2'-dimethyl[1,1'-biphenyl]-4-yl]azo]-, disodium salt Under review
6232-56-0 Diperse Orange 5 Rescinded - July 2017
6250-23-3 Disperse Yellow 23 Under review
6253-10-7 Disperse Orange 13 Under review
6300-37-4 Disperse Yellow 7 Under review
6368-72-5 2-Naphthalenamine, N-ethyl-1-[[4-(phenylazo)phenyl]azo]- Under review
6407-74-5 Pigment Yellow 60 Rescinded - October 2016
6407-78-9 Solvent Yellow 18 Rescinded - October 2016
6420-06-0 1-Naphthalenesulfonic acid, 4-hydroxy-3-[[4'-[(1-hydroxy-5-sulfo-2-naphthalenyl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]-, disodium salt Under review
6465-02-7 Carbamic acid, [4-[[4-[(4-hydroxyphenyl)azo]-2-methylphenyl]azo]phenyl]-, methyl ester Rescinded - July 2017
6535-42-8 Solvent Red 3 Rescinded - October 2016
15958-27-7 Propanenitrile, 3-[[4-[(4-nitrophenyl)azo]phenyl][2-[[(phenylamino)carbonyl]oxy]ethyl]amino]- Rescinded - July 2017
19745-44-9 Propanenitrile, 3-[4-[(5-nitro-2-thiazolyl)azo](2-phenylethyl)amino]- Rescinded - July 2017
21811-64-3 Disperse Yellow 68 Under review
24610-00-2 Benzonitrile, 2-[[4-[(2-cyanoethyl)(2-phenylethyl)amino]phenyl]azo]-5-nitro- Rescinded - July 2017
25150-28-1 Propanenitrile, 3-[[4-[(6,7-dichloro-2-benzothiazolyl)azo]phenyl] ethylamino]- Rescinded - July 2017
28824-41-1 Propanenitrile, 3-[[4-[(4,6-dibromo-2-benzothiazolyl)azo]phenyl]ethylamino]- Rescinded - July 2017
29398-96-7 Pigment Brown 22 Under review
31030-27-0 Benzenamine, 4-[(2-chloro-4-nitrophenyl)azo]-N-ethyl-N-(2-phenoxyethyl)- Rescinded - July 2017
33979-43-0 Propanenitrile, 3-[[2-(acetyloxy)ethyl][4-[(5,6-dichloro-2-benzothiazolyl)azo]phenyl]amino]- Rescinded - July 2017
41362-82-7 Propanenitrile, 3-[[4-[(5,6-dichloro-2-benzothiazolyl)azo]phenyl]methylamino]- Rescinded - July 2017
42852-92-6 Acetamide, N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-4-methoxy-5-[(phenylmethyl)-2-propenylamino]phenyl]- Rescinded - July 2017
55252-53-4 Acetamide, N-[2-[(2-cyano-6-iodo-4-nitrophenyl)azo]-5-(diethylamino)phenyl]- Rescinded - July 2017
56532-53-7 Acetamide, N-[2-[(2,6-dicyano-4-nitrophenyl)azo]-5-(dipropylamino)phenyl]- Rescinded - July 2017
59709-10-3 Pyridinium, 1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]-, acetate Rescinded - October 2016
61799-13-1 3-Pyridinecarbonitrile, 5-[(2-cyano-4-nitrophenyl)azo]-2-[(2-hydroxyethyl)amino]-4-methyl-6-[[3-(2-phenoxyethoxy)propyl]amino]- Rescinded - July 2017
63133-84-6 1(2H)-Quinolineethanol, 6-[(2-chloro-4,6-dinitrophenyl)azo]-3,4-dihydro-2,2,4,7-tetramethyl- Rescinded - July 2017
63134-15-6 Acetamide, N-[5-(dipropylamino)-2-[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]azo]phenyl]- Rescinded - July 2017
63833-78-3 3-Pyridinecarbonitrile, 5-[(2-cyano-4-nitrophenyl)azo]-6-[(2-hydroxyethyl)amino]-4-methyl-2-[[3-(2-phenoxyethoxy)propyl]amino]- Rescinded - July 2017
68214-66-4 Carbamic acid, [2-[(2-chloro-4-nitrophenyl)azo]-5-(diethylamino)phenyl]-, 2-ethoxyethyl ester Rescinded - July 2017
68400-36-2 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-6-[[4'-[(4-hydroxyphenyl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]-3-[(4-nitrophenyl)azo]-, disodium salt Under review
68516-64-3 Propanenitrile, 3-[[2-(acetyloxy)ethyl][4-[(2-chloro-4-nitrophenyl)azo]-3-methylphenyl]amino]- Rescinded - July 2017
68877-63-4 Acetamide, N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-[(2-cyanoethyl)-2-propenylamino]-4-methoxyphenyl]- Rescinded - July 2017
70210-08-1 2-Naphthalenesulfonamide, N-[2-(acetyloxy)ethyl]-6-hydroxy-N-methyl-5-[[4-(phenylazo)phenyl]azo]- Under review
70660-55-8 1-Naphthalenamine, 4-[(2-bromo-4,6-dinitrophenyl)azo]-N-(3-methoxypropyl)- Rescinded - July 2017
71720-89-3 2-Naphthalenesulfonic acid, 5-[[4-(4-cyclohexylphenoxy)-2-sulfophenyl]azo]-6-[(2,6-dimethylphenyl)amino]-4-hydroxy-, disodium salt Rescinded - October 2016
72828-63-8 Benzonitrile, 2-[[4-[[2-(acetyloxy)ethyl]butylamino]-2-methylphenyl]azo]-3-bromo-5-nitro- Rescinded - July 2017
72828-64-9 1,3-Benzenedicarbonitrile, 2-[[4-[[2-(acetyloxy)ethyl]butylamino]-2-methylphenyl]azo]-5-nitro- Rescinded - July 2017
73003-64-2 2,4,10-Trioxa-7-azaundecan-11-oic acid, 7-[4-[(2,6-dichloro-4-nitrophenyl)azo]-3-methylphenyl]-3-oxo-, methyl ester Rescinded - July 2017
73398-96-6 3-Pyridinecarbonitrile, 5-[(9,10-dihydro-9,10-dioxo-1-anthracenyl)azo]-2,6-bis[(2-methoxyethyl)amino]-4-methyl- Rescinded - July 2017
73528-78-6 3-Pyridinecarbonitrile, 5-[[4-[(2,6-dichloro-4-nitrophenyl)azo]-2,5-dimethoxyphenyl]azo]-2,6-bis[(2-methoxyethyl)amino]-4-methyl- Rescinded - October 2016
74336-60-0 Pigment Red 251 Rescinded - October 2016
78952-70-2 Butanamide, 2-[[3,3'-dichloro-4'-[[1-[[(2-chlorophenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2,4-dimethylphenyl)-3-oxo- Rescinded - December 2014
79542-46-4 Acetamide, N-[4-chloro-2-[2-(2-chloro-4-nitrophenyl)azo]-5-[(2-hydroxy-3-phenoxypropyl)amino]phenyl]- Rescinded - July 2017
83027-51-4 1,7-Naphthalenedisulfonic acid, 6-[[2-(4-cyclohexylphenoxy)phenyl]azo]-4-[[(2,4-dichlorophenoxy)acetyl]amino]-5-hydroxy-, disodium salt Rescinded - October 2016
83027-52-5 1,7-Naphthalenedisulfonic acid, 6-[[2-(2-cyclohexylphenoxy)phenyl]azo]-4-[[(2,4-dichlorophenoxy)acetyl]amino]-5-hydroxy-, disodium salt Rescinded - October 2016
83249-47-2 Acetamide, N-[2-[(2-bromo-6-cyano-4-nitrophenyl)azo]-5-(dipropylamino)phenyl]- Rescinded - July 2017
83249-49-4 Benzonitrile, 3-bromo-2-[[4-(diethylamino)-2-methylphenyl]azo]-5-methyl- Rescinded - July 2017
83249-53-0 Methanesulfonamide, N-[2-[(2-bromo-6-cyano-4-methylphenyl)azo]-5-(diethylamino)phenyl]- Rescinded - July 2017
83249-54-1 Methanesulfonamide, N-[2-[(2-bromo-6-cyano-4-methylphenyl)azo]-5-(dipropylamino)phenyl]- Rescinded - July 2017
85005-63-6 2-Naphthalenecarboxamide, 4-[(2,4-dinitrophenyl)azo]-3-hydroxy-N-phenyl- Rescinded - October 2016
85392-21-8 3-Pyridinecarbonitrile, 5-[[2-chloro-4-(phenylazo)phenyl]azo]-2,6-bis[(3-methoxypropyl)amino]-4-methyl- Rescinded - October 2016
90218-20-5 Benzenesulfonic acid, 5-amino-2,4-dimethyl-, diazotized, coupled with diazotized 2,4-, 2,5-and 2,6-xylidine and 4-[(2,4-dihydroxyphenyl)azo]benzenesulfonic acid, sodium salts Rescinded - October 2016
90459-02-2 2,7-Naphthalenedisulfonic acid, 5-amino-4-hydroxy-3-[[6-sulfo-4-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenyl]azo]-, diazotized, coupled with diazotized 4-nitrobenzenamine and resorcinol, potassium sodium salts Rescinded - October 2016
90729-40-1 3-Pyridinecarbonitrile, 1-butyl-5-[[4-(4-chlorobenzoyl)-2-nitrophenyl]azo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo- Rescinded - July 2017
93805-00-6 MMMP Under review
94199-57-2 2-Naphthalenecarboxamide, N-(2-ethoxyphenyl)-3-hydroxy-4-[(2-nitrophenyl)azo]- Rescinded - October 2016
114910-04-2 1-Naphthalenediazonium, 4-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-6-sulfo-, chloride, reaction products with formaldehyde and salicylic acid, ammonium sodium salts Rescinded - October 2016
127126-02-7 Propanenitrile, 3-[[2-(acetyloxy)ethyl][4-[(6,7-dichloro-2-benzothiazolyl)azo]phenyl]amino]- Rescinded - July 2017
Consumer Product SNAc Review Group
CAS RN
(in format,
XXXXX-XX-X) or Confidential Identifier (in format, XXXXX-X)
Chemical substances Review status
64-67-5 Diethyl sulfate Proposed amendment - February 2017
77-78-1 Dimethyl sulfate Proposed amendment - February 2017
79-46-9 2-Nitropropane Proposed amendment - February 2017
93-15-2 Methyl eugenol Proposed amendment - February 2017
111-77-3 DEGME Proposed amendment - November 2017
2426-08-6 n-BGE

Proposed amendment - February 2017

3445-11-2 2-Pyrrolidinone, 1-(2-hydroxyethyl)-

Proposed amendment - January 2017

7328-97-4 TGOPE

Proposed amendment - January 2017

7758-01-2 Potassium bromate Proposed amendment - January 2017
14035-94-0 Dimethyl-2-methyl glutarate Under review
17913-76-7 2,4,7,9-Tetramethyl-4,7-decanediol Under review
37237-76-6 Poly[oxy(methyl-1,2-ethanediyl)], α,α′,α″-1,2,3- propanetriyltris[ω-(oxiranylmethoxy)- Under review
53306-54-0 1,2-Benzenedicarboxylic acid, bis(2-propylheptyl) ester Under review
68664-06-2 Phosphonic acid, P-methyl-, diphenyl ester, polymer with 4,4'-(1-methylethylidene)bis[phenol] Rescinded - September 2013
68956-82-1 Resin acids and Rosin acids, cobalt salts Under review
72102-55-7 MAPBAP acetate Proposed amendment - January 2017
87855-59-2 Acetamide, N,N'-(ethenylmethylsilylene)bis[N-ethyl- Under review
90622-46-1 Alkanes, C14-16 Under review
98859-60-0 Fatty acids, C16_19 and C19-unsatd., esters with acetaldehyde-formaldehyde reaction byproducts Under review
128275-31-0 2H-Isoindole-2-hexaneperoxoic acid, 1,3-dihydro-1,3-dioxo- Under review
164462-16-2 Alanine, N,N-bis(carboxymethyl)-, trisodium salt Under review
216173-24-9 Cyclohexane, bis(isocyanatomethyl)-homopolymer Under review
495403-02-6 Siloxanes and Silicones, 3-[(2-aminoethyl)amino]-2-methylpropyl Me, di-Me, reaction products with N,N,N-trimethyloxiranemethanaminium chloride Under review
670241-72-2 Benzoic acid, nonyl ester, branched and linear Under review
671756-61-9 1-Tetradecanesulfonic acid, (dimethylphenyl)- Under review
676143-36-5 1-Hexadecanesulfonic acid, (dimethylphenyl)- Under review
857892-58-1 Oxirane, [[(2-ethylhexyl)oxy]methyl]-, reaction products with polyethylene glycol ether with 2,4,7,9-tetramethyl-5-decyne-4,7-diol (2:1) Under review
932742-30-8 Dodecanoic acid, 3-[[3-[[[2,2-dimethyl-3-[(1-oxododecyl)oxy]propylidene]amino]methyl]-3,5,5-trimethylcyclohexyl]imino]-2,2-dimethylpropyl ester Under review
1224429-82-6 Phosphoric acid, mixed esters with polyethylene glycol and 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-octanol, ammonium salts Under review
1253391-53-5 Cyclohexane, 1,3-bis(isocyanatomethyl)-, polymer with 1,4-bis(isocyanatomethyl)cyclohexane Under review
18485-8 2-Propenoic acid, 2-methyl-, 2-methylpropyl ester, polymer with butyl 2-propenoate, ethenylbenzene, 2-hydroxyethyl 2-propenoate, 2-oxiranylmethyl 2-methyl-2-propenoate and rel-(1R,2R,4R)-1,7,7-trimethylbicylco[2.2.1]hept-2-yl 2-propenoate, bis(1,1-dimethylpropyl)peroxide and 1,1-dimethylpropyl 2-ethlyhexaneperoxoate-initiated Under review
18563-5 2-Propenoic acid, 2-methyl-, alkyl ester, polymer with ethenylbenzene, methyl 2-methyl-2-propenoate and 2-oxiranylmethyl 2-methyl-2-propenoate, tert-Bu peroxide-initiated Under review
18309-3 2-Propenoic acid, 2-methyl-, alkyl ester, polymer with perfluoroalkylethyl 2-methyl-2-propenoate and vinyl chloride Rescinded - July 2013
18277-7 5,5′-(Polyalkenylalkanediyl)bis(3-substituted-4H-1,2,4 triazole) Under review
18475-7 Alkanediol, reaction products with phosphorus oxide (P2O5), polyfluoro-1-alkanol, -ammonium salts Under review
18143-8 Alkyl dioic acid, polymer with carbonic dichloride and carbopolycyclic diol, substituted phenyl ester Under review
18215-8 Aromatic isocyanate polymer, alkoxy-alkylamine-blocked Under review
18227-2 Carbopolycyclic diol polymer with carbonic dichloride and substituted phenol ester Under review
18187-7 Fatty acids, esters with polyalkanol Under review
18304-7 Fatty acids, reaction products with alkanolamine and alkyloxide Under review
18178-7 Fatty acids, unsatd., dimers, polymers with fatty acids,polyethylene-polyamine and polyethylenepolyamine, compds. with unsatd. fatty acid trimers Under review
17122-4 Oxirane, polymer, monoalkyl ether Rescinded - February 2012
16329-3 Poly(oxy-alkanediyl), α-(carboxy-oxo-alkenyl)-ω-hydroxy-alkyl ethers, Under review
18326-2 Tall oil acids, reaction products with dialkyleneamine and acid anhydride, compounds with polyalkylene glycol hydrogen maleate alkyl ethers Under review
High Hazard, Not in Commerce Substances SNAc Review Group
CAS RN Chemical substances Review status
55-18-5 Ethanamine, N-ethyl-N-nitroso- Amended – March 2026
58-38-8 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]- Amended – March 2026
59-88-1 Hazine, phenyl-, monohydrochloride Amended – March 2026
60-35-5 Acetamide Amended – March 2026
62-50-0 Methanesulfonic acid, esthyl ester Amended – March 2026
62-55-5 Ethanethioamide Amended – March 2026
66-27-3 Methanesulfonic acid, methyl ester- Amended – March 2026
75-25-2 Methane, tribomo- Amended – March 2026
76-01-7 Ethane, pentachloro- Amended – March 2026
76-60-8 Phenol, 4,4' -(3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-3-methyl-, S,S-dioxide Amended – March 2026
77-52-1 Urs-12-en-28-oic acid, 3-hydroxy-, (3β)- Amended – March 2026
78-88-6 1-Propene, 2,3-dichloro- Amended – March 2026
79-00-5 Ethane, 1,1,2-trichloro- Amended – March 2026
79-07-2 Chloroacetamide Amended – March 2026
79-16-3 Acetamide, N-methyl- Amended – March 2026
87-10-5 Benzamide, 3,5-dibromo-N-(4-bromophenyl)-2-hydroxy- Amended – March 2026
93-46-9 1,4-Benzenediamine, N,N'-di-2-naphthalenyl- Amended – March 2026
94-58-6 1,3-Benzodioxole, 5-propyl- Amended – March 2026
96-09-3 Oxirane, phenyl- Amended – March 2026
96-18-4 Propane, 1,2,3-trichloro Amended – March 2026
96-66-2 Phenol, 4,4' -thiobis[2-(1,1-dimethylethyl)-6-methyl- Amended – March 2026
100-63-0 Hydrazine, phenyl-, monohydrochloride Amended – March 2026
101-61-1 Benzenamine, 4,4'-methylnenebis [N,N-dimethyl-] Amended – March 2026
106-87-6 7-Oxabicyclo[4.1.0]heptane, 3-oxiranyl- Amended – March 2026
107-05-1 3-Chloropropene Amended – March 2026
110-88-3 1,3,5-Trioxane Amended – March 2026
115-28-6 Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, 1,2,5,6,7-hexachloro- Amended – March 2026
116-14-3 Ethene, tetrafuloro- Amended – March 2026
116-66-5 Musk Moskene Amended – March 2026
117-82-8 1,2-Benzenedicarboxylic acid, bis(2-methoxyethyl) ester (DMEP) Amended – March 2026
122-60-1 Oxirane, (phenoxymethyl)- Amended – March 2026
123-39-7 Formamide, N-methyl- Amended – March 2026
123-73-9 2-Butenal, (E)- Amended – March 2026
131-18-0 1,2-Benzenedicarboxylic acid, dipentyl ester Amended – March 2026
131-52-2 Phenol, pentachloro-, sodium salt Amended – March 2026
132-61-6 9H-Carbazole-3-carboxamide, N-(4-chlorophenyl)-2-hydroxy- Amended – March 2026
133-49-3 Benzenethiol, pentachloro- Amended – March 2026
135-20-6 Benzenamine, N-hydroxy-N-nitroso-, ammonium salt Amended – March 2026
136-35-6 1-Triazene, 1,3-diphenyl- Amended – March 2026
141-90-2 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- Amended – March 2026
145-39-1 Benzene, 1-(1,1-dimethylethyl)-3,4,5-trimethyl-2,6-dinitro- Amended – March 2026
331-39-5 2-Propenoic acid, 3-(3,4-dihydroxyohenyl)- Amended – March 2026
440-17-5 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride Amended – March 2026
475-71-8 Pigment Yellow 24 Amended – March 2026
492-80-8 Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-] Amended – March 2026
569-61-9 Benzenamine, 4-[(4-aminophenyl)(4-imino-2,5cyclohexadien-1-ylidene)methyl]-, monohydrochloride Amended – March 2026
591-78-6 2-Hexanone Amended – March 2026
593-60-2 Ethene, bromo- Amended – March 2026
603-33-8 Triphenylbismuth Amended – March 2026
603-48-5 Benzenamine, 4,4',4"-methylidynetris[N,N-dimethyl- Amended – March 2026
606-20-2 Benzene, 2-methyl-1,3-dinitro Amended – March 2026
608-71-9 Phenol, pentabromo- Amended – March 2026
615-28-1 1,2-Benzenediamine, dihydrochloride Amended – March 2026
626-39-1 1, 3, 5 - Tribromobenzene Amended – March 2026
823-40-5 1,3-Benzenediamine, 2-methyl- Amended – March 2026
944-61-6 Tetrachloroveratrole Amended – March 2026
1000-05-1 Tetrasiloxane, 1,1,3,3,5,5,7,7-octamethyl- Amended – March 2026
1120-71-4 1,2-Oxathiolane, 2,2-dioxide- Rescinded - September 2025
1154-59-2 Benzamide, 3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxy-(3,3',4',5-tetrachlorosalicylanilide) Amended – March 2026
1176-74-5 Bromophthalein Magenta E Amended – March 2026
1325-85-5 1-Naphthalenemethanol, α,α-bis[4-(dimethylamino)phenyl]-4-(methylphenylamino)- Amended – March 2026
1325-86-6 Solvent Blue 5 Amended – March 2026
1326-05-2 Eosine Lead Lake Amended – March 2026
1326-49-4 C.I. Sulphur Orange 1 Amended – March 2026
1694-09-3 Benzenemethanaminium, N-[4-[[4-(dimethylamino)phenyl][4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-3-sulfo-, hydroxide, inner salt, sodium salt- Amended – March 2026
2062-78-4 2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro- Amended – March 2026
2379-75-1 Benzo[b]thiophen-3(2H)-one, 5-chloro-2-(5-chloro-4,7-dimethyl-3-oxobenzo[b]thien-2(3H)-ylidene)-4,7-dimethyl- Amended – March 2026
2538-84-3 Anthra[9,1,2-cde]benzo[rst]pentaphene-5,10-diol, 16,17-dimethoxy-, bis(hydrogen sulfate), disodium salt Amended – March 2026
2746-81-8 Heptanoic acid, 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester Amended – March 2026
3271-22-5 1,3,5-Triazine, 2,4-dimethoxy-6-(1-pyrenyl)- Amended – March 2026
3296-90-0 1,3-Propanediol, 2,2-bis(bromomethyl)- Amended – March 2026
3687-67-0 3H-Indol-3-one, 5-bromo-2-(9-chloro-3-oxonaphtho[1,2-b]thien-2(3H)-ylidene)-1,2-dihydro- Amended – March 2026
3767-68-8 9,10-Anthracenedione, 1-amino-4-(2-benzothiazolylthio)- Amended – March 2026
4170-30-3 2-Butenal Amended – March 2026
4395-65-7 Disperse Blue 19 Amended – March 2026
6257-39-2 [1,1'-Biphenyl]-4-ol, 3,4',5-tris(1,1-dimethylethyl)- Amended – March 2026
6371-23-9 Benzo[b]thiophen-3(2H)-one, 5,7-dichloro-2-(6-chloro-4-methyl-3-oxobenzo[b]thien-2(3H)-ylidene)-4-methyl- Amended – March 2026
6373-31-5 Naphth[2,3-c]acridine-5,8,14(13H)-trione, 6,10,12-trichloro- Amended – March 2026
6408-50-0 9,10-Anthracenedione, 1-(methylamino)-4-[(3-methylphenyl)amino]- Amended – March 2026
6409-68-3 2-Anthracenecarboxaldehyde, 1-amino-9,10-dihydro-9,10-dioxo-, 2-[(1-amino-9,10-dihydro-9,10-dioxo-2-anthracenyl)methylene]hydrazone Amended – March 2026
6417-38-5 Naphth[2,3-c]acridine-10-carboxamide, N-[5-(benzoylamino)-9,10-dihydro-9,10-dioxo-1-anthracenyl]-5,8,13,14-tetrahydro-5,8,14-trioxo- Amended – March 2026
6786-83-0 Solvent Blue 4 Proposed amendment - February 2017
10034-93-2 Hydrazine, sulfate (1:1) Amended – March 2026
10046-00-1 Hydroxylamine, sulfate (1:1) (salt) Amended – March 2026
10448-09-6 Phenyl - D4 Proposed amendment - February 2017
12789-03-6 Chlordane (technical grade) Maintained – March 2026
13463-39-3 Nickel carbonyl (Ni(CO)4), (T-4)- Amended – March 2026
13840-56-7 Boric acid (H3BO3), sodium salt Amended – March 2026
14295-43-3 Pigment Red 88 Amended – March 2026
15545-48-9 Urea-N'-(3-chloro-4-methylphenyl)-N,N-dimethyl- Amended – March 2026
15958-61-9 9,10-Anthracenedione, 1-[[4-(phenylsulfonyl)phenyl]amino]- Amended – March 2026
16834-13-2 21H,23H-Porphine, 5,10,15,20-tetra-4-pyridinyl- Amended – March 2026
19163-98-5 Benzoxazolium, 2-[3-[5,6-dichloro-1-ethyl-1,3-dihydro-3-(3-sulfopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-3-ethyl-, hydroxide, inner salt Amended – March 2026
23077-61-4 9H-Carbazole-1-carboxamide, N-(4-chlorophenyl)-2-hydroxy- Amended – March 2026
24169-02-6 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate Amended – March 2026
24602-86-6 Morpholine, 2,6-dimethyl-4-tridecyl Amended – March 2026
25321-14-6 Benzene, methyldinitro- Amended – March 2026
25376-45-8 1,3-Benzenediamine, ar-methyl Amended – March 2026
25857-05-0 Hexanedioic acid, bis[2-[[4-(2,2-dicyanoethenyl)-3-methylphenyl]ethylamino]ethyl] ester Amended – March 2026
26447-14-3 Oxirane, [(methylphenoxy)methyl]- Amended – March 2026
27341-33-9 9,10-Anthracenedione, 1-amino-4-[(methoxyphenyl)amino]- Amended – March 2026
28118-10-7 1H-Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propenyl]-1-ethyl-3-(3-sulfobutyl)-, hydroxide, inner salt Amended – March 2026
36294-24-3 Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, ethyl ester Amended – March 2026
38465-55-3 Nickel, bis[1-[4-(dimethylamino)phenyl]-2-phenyl-1,2-ethenedithiolato(2-)-S,S']- (BDN) Amended – March 2026
39156-41-7 1,3-Benzenediamine, 4-methoxy-, sulfate (1:1) Amended – March 2026
40615-36-9 Dimethoxytriltyl Chloride Amended – March 2026
42479-88-9 [1,1'-Biphenyl]-4-ol, 3,4'-bis(1,1-dimethylethyl)- Amended – March 2026
52591-25-0 9,10-Anthracenedione, 2,2' -(1,3,4-oxadiazole-2,5-diyl)bis[1-amino- Amended – March 2026
52671-38-2 9,10-Anthracenedione, 2,2' -[1,4-phenylenebis(1,3,4-oxadiazole-5,2-diyl)]bis[1-amino- Amended – March 2026
53184-75-1 Phosphorous acid, (1-methylethylidene)di-4,1-phenylene tetrakis[(3-ethyl-3-oxetanyl)methyl] ester Amended – March 2026
54079-60-6 Propanedinitrile, [[4-[[2-(2-cyclohexylphenoxy)ethyl]ethylamino]-2-methylphenyl]methylene]- Amended – March 2026
54243-60-6 9,10-Anthracenedione, 1-amino-4-hydroxy-2-(4-methoxyphenoxy)- Amended – March 2026
55290-64-7 1,4-Dithiin, 2,3-dihydro-5,6-dimethyl-, 1,1,4,4-tetraoxide Amended – March 2026
56307-70-1 Benzenediazonium, 2-methoxy-4-nitro-, salt with naphthalenedisulfonic acid (2:1) Amended – March 2026
58019-27-5 Anthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione, diamino- Amended – March 2026
58161-93-6 Benzoic acid, 4-[1-[[(2,4-dichlorophenyl)amino]carbonyl]-3,3-dimethyl-2-oxobutoxy]- (BADAC) Amended – March 2026
59583-77-6 Carbamic acid, (3,4-dichlorophenyl)-, 2-[butyl[4-(2,2-dicyanoethenyl)-3-methylphenyl]amino]ethyl ester Amended – March 2026
60352-98-9 1-Propanaminium, 3-[[4-[(2,4-dimethylphenyl)amino]-9,10-dihydro-9,10-dioxo-1-anthracenyl]amino]-N,N,N-trimethyl-, methylsulfate (PDDAM) Amended – March 2026
63281-10-7 3-Pyridinecarbonitrile, 5-[[2-chloro-4-(methylsulfonyl)phenyl]azo]-4-methyl-2,6-bis[[3-(2-phenoxyethoxy)propyl]amino]- Amended – March 2026
63467-15-2 1(2H)-Quinolinepropanamide, 6-(2,2-dicyanoethenyl)-3,4-dihydro-2,2,4,7-tetramethyl-N-phenyl- Amended – March 2026
63467-19-6 Propanedinitrile, [[1,2,3,4-tetrahydro-2,2,4-trimethyl-1-[2-[[(phenylamino)carbonyl]oxy]ethyl]-6-quinolinyl]methylene]- Amended – March 2026
64086-95-9 9,10-Anthracenedione, 1-amino-2-bromo-4-[[4-[(1-methylethyl)amino]-6-phenyl-1,3,5-triazin-2-yl]amino]- Amended – March 2026
64086-96-0 9,10-Anthracenedione, 2-acetyl-1-amino-4-[[4-[(1-methylethyl)amino]-6-phenyl-1,3,5-triazin-2-yl]amino]- Amended – March 2026
64111-81-5 Trichloro - 2 - hydroxyldiphenyl Amended – March 2026
64325-78-6 Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl) phenylmethyl]-2'-deoxy- (DMTBA) Amended – March 2026
64742-66-1 Naphtha (petroleum), catalytic dewaxed Amended – March 2026
67219-55-0 Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- Amended – March 2026
68227-79-2 Benzenesulfonic acid, 2-[[9,10-dihydro-4-[(4-methylphenyl)amino]-9,10-dioxo-1-anthracenyl]amino]-5-methyl-, monoammonium salt Amended – March 2026
68443-10-7 Amines, C18-22-tert-alkyl, ethoxylated (ATAE) Rescinded – August 2024
68512-30-1 Phenol, methylstyrenated Maintained – March 2026
68551-44-0 Fatty acids, C6-19-branched, zinc salts (FAZ) Proposed rescission - January 2017
68583-58-4 Ethanamine, N-ethyl-N-hydroxy-, reaction products with hexamethylcyclotrisiloxane, silica and 1,1,1-trimethyl-N-(trimethylsilyl)silanamine (HMSSA) Rescinded – July 2024
68910-11-2 Benzenemethanol, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, reaction products with 1,3,5-trimethylbenzene Amended – March 2026
68938-51-2 Siloxanes and Silicones, 3-cyanopropyl Me, di-Me Amended – March 2026
69430-47-3 MDnM - hydride Proposed rescission - January 2017
69695-75-6 9,10-Anthracenedione, 1-amino-4-[[3-[(dimethylamino)methyl]phenyl]amino]-, monohydrochloride Amended – March 2026
69898-66-4 5-Isobenzofurancarboxylic acid, 3-[4-(diethylamino)-2-ethoxyphenyl]-3-(1-ethyl-2-methyl-1H-indol-3-yl)-1,3-dihydro-1-oxo-, ethyl ester Amended – March 2026
69898-67-5 5-Isobenzofurancarboxylic acid, 1-[4-(diethylamino)-2-ethoxyphenyl]-1-(1-ethyl-2-methyl-1H-indol-3-yl)-1,3-dihydro-3-oxo-, ethyl ester Amended – March 2026
70161-19-2 Acid Green 40:1 Amended – March 2026
70776-86-2 2-Butanone, 4-[[[1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl](3-oxo-3-phenylpropyl)amino]-, [1R-(1α,4aβ,10aα)]- (BODPA) Amended – March 2026
72102-56-8 Methylium, [4-(dimethylamino)phenyl]bis[4-(ethylamino)-3-methylphenyl]-, chloride Amended – March 2026
72102-64-8 Methylium, bis[4-(dimethylamino)phenyl][4-(ethylamino)-3-methylphenyl]-, chloride Amended – March 2026
72318-87-7 Phenol, [[[3-(dimethylamino)propyl]amino]methyl]-, isobutylenated Amended – March 2026
72749-91-8 Benzenesulfonic acid, [(9,10-dihydro-9,10-dioxo-1,4-anthracenediyl)diimino]bis[(1,1-dimethylethyl)-, sodium salt Amended – March 2026
72812-39-6 Methylium, bis(4-amino-3,5-dimethylphenyl)(2,6-dichlorophenyl)-, phosphate (1:1) Amended – March 2026
72828-93-4 1-Propanaminium, 3-[[9,10-dihydro-4-[(4-methylphenyl)amino]-9,10-dioxo-1-anthracenyl]amino]-N,N,N-trimethyl-, methyl sulphate Amended – March 2026
73398-86-4 Pyridine, 4-(3-chloro-5-propylphenyl)- Amended – March 2026
73398-87-5 Pyridine, 4-(4-chloro-3-propylphenyl)- Amended – March 2026
75908-83-7 Benzenesulfonic acid, oxybis[(1,1,3,3-tetramethylbutyl)-, dipotassium salt Amended – March 2026
83006-67-1 Benzenesulfonic acid, 2,2'-[(9,10-dihydro-5,8-dihydroxy-9,10-dioxo-1,4-anthracenediyl)diimino]bis[5-(1,1-dimethylethyl)-, disodium salt (ADIBSS) Amended – March 2026
83721-47-5 Methanesulfonamide, 1-chloro-N-[2,3,4-trichloro-6-(2,4-dichlorophenoxy)phenyl]-, sodium salt Amended – March 2026
83721-48-6 Methanesulfonamide, 1-chloro-N-[2,3,4,5-tetrachloro-6-(2,4-dichlorophenoxy)phenyl]-, sodium salt Amended – March 2026
83968-86-9 9,10-Anthracenedione, 1-amino-4-[[3-[(dimethylamino)methyl]phenyl]amino]-, monoacetate Amended – March 2026
85186-47-6 Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, salt with mono-C10-14-alkylbenzenesulfonic acid (1:1) Amended – March 2026
85702-64-3 3H-Indol-3-one, 5,7-dibromo-2-(5-bromo-7-chloro-1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro- Amended – March 2026
86551-61-3 Butanamide, 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]-N-[4-(2-formylhydrazino)phenyl]- Amended – March 2026
90268-98-7 Carbonic acid disodium salt, reaction products with aniline,4-nitrobenzenamine, p-phenylenediamine, sodium sulfide, sulfur and p-toluidine Amended – March 2026
91696-90-1 [2,6'-Bibenzothiazole]-7-sulfonic acid, 2'-(4-aminophenyl)-6-methyl-, diazotized, coupled with diazotized 4-aminobenzenesulfonic acid and resorcinol, sodium salts Amended – March 2026
93384-84-0 Naphthalenesulfonic acid, reaction products with formaldehyde and hydroxybenzenesulfonic acid, ammonium salts Amended – March 2026
93918-79-7 Carbamic acid, cyclohexyl-, nitrilotri-2,1-ethanediyl ester Rescinded – August 2024
94248-26-7 Methanesulfonamide, 1-chloro-N-(2-phenoxyphenyl)-, pentachloro deriv., sodium salt Amended – March 2026
101200-53-7 Pyridine, 2-[3-(3-chlorophenyl)propyl]- (CPPP) Amended – March 2026
103122-66-3 Carbamic acid, [(2-methylpropoxy)thioxomethyl]-, ethyl ester- Amended – March 2026
103331-97-1 Fatty acids, tallow, hydrogenated, [6-[bis(methoxymethyl)amino]-1,3,5-triazine-2,4-diyl]bis[[(methoxymethyl)imino]methylene] ester Amended – March 2026
103331-98-2 Fatty acids, tallow, hydrogenated, hexaesters with 2-[[[4-[[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl](hydroxymethyl)amino]-6-[(hydroxymethyl)(methoxymethyl)amino]-1,3,5-triazin-2-yl](methoxymethyl)amino]methoxy]-1,3-propanediol Amended – March 2026
104376-69-4 Formaldehyde, reaction products with branched nonylphenol and xylenol, ethoxylated Amended – March 2026
108004-27-9 1H-Imidazole-1-ethanol, α-(2,4-dichlorophenyl)-α-[2-(2,4-dichlorophenyl)cyclopropyl]-, [1α(R*),2β]- Amended – March 2026
113089-51-3 Alkenes, C12-14, hydroformylation products, distn. residues, ethoxylated propoxylated, dihydrogen phosphates, sodium salts Rescinded - August 2024
113163-36-3 Formaldehyde, reaction products with sulfonated 1,1'-biphenyl and sulfonated terphenyl, sodium salts Amended – March 2026
117310-64-2 Phosphine oxide, (butylphenyl)bis(2,6-dichlorobenzoyl)- Amended – March 2026
119209-64-2 Alkenes, C12-14, hydroformylation products, distn. residues,ethoxylated, dihydrogen phosphates, sodium salts Rescinded - August 2024
124751-15-1 Resin acids and Rosin acids, fumarated, barium salts (RFBS) Under review
125328-28-1 Phenol, 4,4 -(1-methylethylidene)bis-, reaction products with hexakis(methoxymethyl)melamine (PMEI) Amended – March 2026
128683-35-2 Residues (oil sand), atm. Tower Maintained – March 2026
223777-68-2 Benzenesulfonic acid, hydroxydinonyl-, branched, monoammonium salt Amended – March 2026
Nanomaterials SNAc Review Group
CAS RN
(in format,
XXXXX-XX-X) or Confidential Identifier (in format, XXXXX-X)
Chemical substances Review status
640-67-5 Ethanedioic acid, manganese(2++) salt (1:1) Under review
1310-53-8 Germanium dioxide Under review
1345-07-9 Bismuth sulfide (Bi2S3) Under review
9032-43-3 Cellulose sulphate Under review
12068-51-8 Aluminate (AlO2¹-), magnesium (2:1) Under review
12070-10-9 Vanadium carbide (VC) Under review
12070-13-2 Tungsten Carbide Under review
13573-13-2 Vanadate (VO3¹-), magnesium (2:1) Under review
13597-19-8 Cerium vanadium oxide Under review
15365-14-7 Phosphoric acid, iron(2+) lithium salt (1:1:1) Under review
39445-23-3 Calcium magnesium hydroxide (CaMg(OH)4) Rescinded - June 2015
68584-82-7 Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-, hydrolysis products with silica Under review
72319-09-6 Silica gel, fluorinated Rescinded - June 2015
102561-69-3 Ferrate(1-), bis[3,5-bis(1,1-dimethylethyl)-2-(hydroxy-.kappa.O)benzoato(2-)-.kappa.O]-, hydrogen (1:1) Rescinded - June 2015
124343-14-2 Magnesium hydroxide sulfate (Mg6(OH)10(SO4)) Under review
182442-95-1 Lithium cobalt manganese nickel oxide Under review
207691-99-4 Rutile, tin zinc, potassium-doped Rescinded - June 2015
346417-97-8 Cobalt lithium manganese nickel oxide Under review
389623-01-2 Rutile, tin zinc, calcium-doped Rescinded - June 2015
389623-07-8 Rutile, tin zinc, sodium-doped Rescinded - June 2015
849036-06-2 Silane, trimethoxypropyl-, hydrolysis products with silica Under review
923954-49-8 Tin titanium zinc oxide Rescinded - June 2015
18192-3 Alkyl acrylic acid, (alkoxysilyl)alkyl ester, reaction products with silica Under review
18550-1 Cobalt iron manganese oxide, carboxylic acid-modified Under review
18430-7 Metal hydroxy phosphate Under review
Not applicable Multi-wall carbon nanotubes Under review
18040-4 Organic silicone intermediate Under review
18552-3 Potassium titanate Under review
18375-6 Quino[2,3-b]acridine-7, 14-dione, dichloro-5, 12-dihydro-, (1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl derivs. Rescinded - June 2015
18291-3 Short tangled multi-walled carbon nanotubes obtained by catalytical chemical vapour deposition Under review
17953-7 Silane homopolymer Rescinded - June 2015
17891-8 Substituted silylated resorcinol, reaction products with trimethoxysilane-silica hydrolysis products Under review
17933-5 Supramolecular complex of di(bisalkylsulfosuccinate) barium salt with barium hydrogen phosphate (2:1) Under review
Remaining Existing Substances SNAc Review Group
CAS RN Chemical substances Review status
62-56-6 Thiourea Proposed amendment - January 2017
72-43-5 Methoxychlor Amended – March 2021
75-56-9 Methyloxirane Proposed amendment - January 2017
87-86-5 Pentachlorophenol Amended – March 2021
88-72-2 2-Nitrotoluene Under review
90-94-8 Michler's ketone Proposed amendment - January 2017
100-44-7 Benzyl chloride Proposed amendment - January 2017
106-88-7 Ethyloxirane Proposed amendment - January 2017
106-89-8 Epichlorohydrin Amended – March 2025
110-49-6 2-Methoxyethanol acetate Under review
111-15-9 2 - Ethoxyethanol acetate Proposed amendment - January 2017
115-96-8 TCEP Proposed amendment - January 2017
120-80-9 Catechol Under review
123-31-9 Hydroquinone Proposed amendment - January 2017
379-52-2 Fluorotriphenyl-stannane Under review
595-90-4 Tetraphenyl-stannane Under review
732-26-3 2,4,6-tri-tert-butylphenol Under review
1314-62-1 Vanadium pentoxide Proposed amendment - January 2017
1344-37-2 C.I. Pigment Yellow 34 Under review
1582-09-8 Trifluralin Amended – March 2021
1897-45-6 Chlorothalonil Amended – March 2021
1912-24-9 Atrazine Amended – March 2021
2425-85-6 Pigment Red 3 Proposed amendment - January 2017
3691-35-8 Chlorophacinone Amended – March 2021
12656-85-8 C.I. Pigment Red 104 Under review
17540-75-9 DTBSBP Proposed amendment - January 2017
Not applicable Pseudomonas aeruginosa (ATCC 31480) Proposed rescission – June 2021
Not applicable Pseudomonas aeruginosa (ATCC 700370) Proposed rescission – June 2021
Not applicable Pseudomonas aeruginosa (ATCC700371) Proposed rescission – June 2021
Remaining New Substances SNAc Review Group
CAS RN
(in format,
XXXXX-XX-X) or Confidential Identifier (in format, XXXXX-X)
Chemical substances Review status
75-10-5 Difluoromethane Rescinded - February 2017
354-33-6 Pentafluoroethane Rescinded - February 2017
406-58-6 1,1,1,3,3-pentafluorobutane Rescinded - February 2017
420-46-2 1,1,1-trifluoroethane Rescinded - February 2017
431-89-0 1,1,1,2,3,3,3-heptafluoropropane Rescinded - February 2017
460-73-1 Propane, 1,1,1,3,3-pentafluoro- Rescinded - February 2017
598-55-0 Carbamic acid, methyl ester Under review
690-39-1 1,1,1,3,3,3-hexafluoropropane Rescinded - February 2017
1962-75-0 1,4-Benzenedicarboxylic acid, 1,4-dibutyl ester Under review
2128-93-0 Methanone, [1,1'-biphenyl]-4-ylphenyl- Under review
2432-74-8 Hexanenitrile, 6-amino- Under review
3115-49-9 Acetic acid, (4-nonylphenoxy)- Under review
13162-05-5 Formamide, N-ethenyl- Under review
15290-77-4 Cyclopentane, 1,1,2,2,3,3,4-heptafluoro- Rescinded - February 2017
23328-71-4 1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride (1:1) Under review
34432-92-3 Benzenamine, N-ethyl-N-[2-[1-(2-methylpropoxy)ethoxy]ethyl]-4-(2-phenyldiazenyl)- Under review
35180-01-9 Chloromethyl (1-methylethyl) carbonate Under review
39142-36-4 Thioimidodicarbonic acid ((HO)C(O)NHC(S)(OH)), C,C'-dibutyl ester Under review
51851-37-7 Silane, triethoxy (3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluoroocyl) Under review
68187-39-3 Oxiranemethanol, C12-14-tert-alkylcarboxylates, reaction products with triethylenetetramine Under review
68412-63-5 Phosphoric acid, C12-15-alkyl esters Under review
68515-51-5 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters Under review
68920-56-9 Clarified oils (petroleum), catalytic cracked, reaction products with cresol and polymethylenepolyphenylene isocyanate Proposed amendment - January 2017
70865-20-2 Benzenesulfonic acid, 4-[[4-[(4-hydroxy-2-methylphenyl)azo]phenyl]amino]-3-nitro-, monosodium salt Under review
71033-08-4 Oxirane, 2,2'-[(1-methylethylidene)bis[4,1-phenyleneoxy[1-(butoxymethyl)-2,1-ethanediyl]oxymethylene]]bis- Under review
72245-02-4 Amines, tallow alkyl, ethoxylated, 2-ethylhexanoates Under review
90076-65-6 Methanesulfonamide, 1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-, lithium salt Under review
91788-83-9 1,2,3,4-Butanetetracarboxylic acid, tetrakis(1,2,2,6,6-pentamethyl-4-piperidinyl) ester Under review
105076-77-5 Acetamide, N-[5-[bis(2-methoxyethyl)amino]-2-[(5-nitro-2,1-benzisothiazol-3-yl)azo]phenyl]- Under review
123464-54-0 Poly(oxy-1,2-ethanediyl), α-[2(or 4)-tetrapropenylphenyl]-ω-hydroxy- Under review
138495-42-8 Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro- Rescinded - February 2017
149879-98-1 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[[(13Z)-1-oxo-13-docosenyl]amino]-, inner salt Under review
188627-10-3 Siloxanes and Silicones, di-Me, [[[3-[(2-aminoethyl)amino]-2-methylpropyl]methoxymethylsilyl]oxy]- and (C13-15-alkyloxy)-terminated Under review
189233-30-5 1-Hexadecanol, manuf. of, distn. lights Under review
190085-41-7 Benzoic acid, 2-hydroxy-, 2-butyloctyl ester Under review
211510-16-6 Benzeneacetic acid, α-oxo-, 1,1'-(oxydi-2-1-ethanediyl) ester Under review
220689-12-3 Phosphonium, tetrabutyl-, salt with 1,1,2,2,3,3,4,4,4-nonafluoro-1-butanesulfonic acid (1:1) Under review
220727-26-4 Octanethioic acid, S-[3-(triethoxysilyl)propyl]ester Under review
237753-63-8 Alcohols, C13-15, reaction products with N-[3-(dimethoxymethylsilyl)-2-methylpropyl]1,2-ethanediamine, glycidol, and hydroxy-terminated di-Me siloxanes Under review
442536-99-4 Benzeneacetic acid, α-oxo-, 2-(2-hydroxyethoxy)ethyl ester Under review
519050-73-8 Fatty acids, C12-16, Me esters, reaction products with ethoxylated diamides from C12-16 fatty acids and ethylenediamine, sulfates (esters), sodium salts Under review
863918-80-3 Siloxanes and silicones, 3-[(2-aminoethyl)amino]-2-methylpropyl Me, di-Me, polymers with Me silsesquioxanes, hydroxy-terminated Under review
882878-48-0 Siloxanes and Silicones, di - Me, Me - 3, 3, 4, 4, 5, 5, 6, 6, 6 - Nonafluorohexyl Under review
921936-12-1 Siloxanes and Silicones, 3-[(2-aminoethyl)amino]propyl Me, di-Me, hydroxy- and methoxy-terminated, polymers with polyethylene-polypropylene glycol bis(2-methyl-2-propen-1-yl) ether Under review
929218-99-5 Siloxanes and Silicones, 3-[(2-aminoethyl)amino]propyl Me, hydroxy-terminated, polymers with hydrogen terminated di-Me siloxanes and polyethylene glycol bis(2-methyl-2-propen-1-yl) ether Under review
959468-05-4 Oxirane, 2-methyl-, polymer with oxirane, ether with 1,2,3-propanetriol (3:1), tris[N-[methyl-3-[[(nonylphenoxy)carbonyl]amino]phenyl]carbamate] Rescinded - February 2015
1001320-38-2 Carbamic acid, [(butylthio) thioxomethyl]-,butyl ester Under review
1013910-41-2 Oxirane, 2-ethyl-, polymer with oxirane, mono-C12-14-sec-alkyl ethers Under review
1022990-65-3 Oxirane, 2-ethyl-, polymer with oxirane, mono-C11-15-sec-alkyl ethers Under review
17878-4 1,2-Propanediol, 3-amino-, dialkyl derivatives Under review
18253-1 1-Octanol, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-, reaction products with phosphorus oxide (P2O5), ammonium salts Under review
14587-7 2-Propenoic acid, 2-alkyl-, oxiranyl-methyl ester polymer with ethenylbenzene, 2-hydroxybutyl 2-propenoate, 2-methylpropyl, 2-propenoate and exo-1,7,7-trimethylbicyclo [2.2.1]hept-2-yl 2-propenoate, 2,2′-azobis[2-methylbutanenitrile]- Under review
18009-0 2-Propenoic acid, 2-alkyl-, oxiranylmethyl ester, polymer with ethenylbenzene,
4-hydroxybutyl 2-propenoate, 2-methylpropyl 2-propenoate and rel-(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl 2-propenoate, bis(1,1-dimethylpropyl) peroxide-initiated
Under review
18097-7 2-Propenoic acid, 2-methyl, alkyl ester, polymer with 1,1-dichloroethene, alkyl 2-methyl-2-propenoate and perfluoroalkyl 2-methyl-2-propenoate Under review
16020-0 2-Propenoic acid, 2-methyl-, oxiranylmethyl ester polymer with alkyl 2-propenoate, ethylbenzene and 2-oxepanone homopolymer 2-[(1-oxo-2-
propenyl)oxy]ethyl ester, 2,2′-azobis[2-methylbutanenitrile]-
Under review
17810-8 2-Propenoic acid, 2-methyl-, oxiranylmethyl ester, polymer with ethenylbenzene, substituted alkyl 2-propenoate, 2-methylalkyl 2-propenoate, and rel-(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl 2-propenoate, tert-Bu ethaneperoxoate-initiated Under review
Not applicable Actinosynnema pretiosum strain 3-459 Rescinded - April 2015
17818-7 Aliphatic alkyl diester of succinic acid Under review
17128-1 Alkanamide, (3,3′-dichloro[1, 1′-biphenyl]-4,4′-diyl)bis(azo)bis[phenylfattyalkylpolyazaalkylidine]- Under review
17556-6 Alkanethioic acid, S-[3-(triethoxysilyl)propyl] ester, hydrolysis products with 2-methyl-alkanediol Under review
17672-5 Alkanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-alkanediol Under review
17915-5 Alkanoic acid, dihydroxy-,2-alkyl ester Under review
Not applicable Avipoxvirus fowlpox virusstrain TBC-FPV Proposed rescission – June 2021
18029-2 Butanedioic acid, 2,3-dihydroxy-, mixed alkyl diesters, (2R,3R)-rel- Rescinded - June 2012
18030-3 Butanedioic acid, 2,3-dihydroxy-, mixed C12-16-alkyl and C13-rich C11-14-isoalkyl diesters, (2R,3R)-rel- Under review
17978-5 Fatty acids, tall-oil, reaction products with alkylamine and 2-propenoic acid Under review
Not applicable Fowlpox virus strain TBC-FPV + modified PSA, B7.l, ICAM-l, LFA-3) Proposed rescission – June 2021
Not applicable genetically engineered Atlantic salmon (Salmo salar) containing a single copy of the opAFP-GHc2 transgene at the EO-1α locus Under review
17849-2 Hexane, 1,6-diisocyanato-, homopolymer, polyethylene glycol mono-Me ether- and perhalo-1-alkanol blocked Rescinded - June 2012
17121-3 Isooctadecanoic acid, reaction products with tetraethylenepentamine, compounds with di-Bu phosphonate-2,2′-dithiobis[ethanol]alkyl substituted
alcohol reaction products, 2,2′-iminobis[ethanol], [N-[3-(C16-18-alkyloxy)propyl]] derivatives and 4(or 5)-methyl-1H-benzotriazol
Under review
16873-7 Modified Yeast Proposed rescission – June 2021
18242-8 Oleic acid, compound with alkaneamine Under review
12748-4 Oxirane, (chloromethyl)-, polymer with α-hydro-ω-hydroxypoly[oxy(methyl-1,2-ethanediyl)] ether with polyol, 4,4′-(1-methylethylidene)bisphenol, 2,2′-[(methylethylidene)bis (4,1-phenyleneoxymethylene)]bisoxirane and methyloxirane polymer with oxirane, 2-aminopropyl methyl ether Under review
Not applicable Pichia species strain Proposed amendment – June 2021
16044-6 Quaternary amide, polymer with 2-propenoic acid, sodium salt, reaction products with disodium (disulfite) Under review
17785-1 Shewanella putrefaciens strain AB3-01 Proposed amendment – June 2021
17825-5 Starch, 2-hydroxyalkyl 2-hydroxy-3-(trimethylammonio)alkyl ether, chloride Under review
Not applicable The Cassie line of transgenic Sus scrofa domestica Under review
17486-8 Thiobacillus W5 consortium Proposed rescission – June 2021
17801-8 Yeast Proposed rescission – June 2021
Not applicable Vaccinia virus (TBC-Wy; NYCBH strain) with modified PSA, B7.1, ICAM-1, LFA-3 Proposed amendment – June 2021

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2026-03-25